HistoMatch - Atlas/Histology Matching
HistoMatch is a powerful, easy-to-use software tool for interactive atlas/histology matching. It supports straightforward digitization of histological preparations, rapid identification, assignment and fitting of the best histological slice containing the brain region of interest to the correspondent atlas slice.
- Histology Slice Digitization
- Smart Atlas Matching
- Intuitive Slice Manipulation
- Rat & Mouse Brain Slices
- High Throughput Analysis
- Easy-To-Use
You can use this powerful tool to further correct atlas-localization discrepancies by histological feedback, and to significantly enhance the insight on the electrophysiological mapping.
HistoMatch offers a user-friendly importing-matching-embedding scenario in a comfortable wizard mode:
- start with a histology glass slide with a matrix of slices
- scan and save a digital image of the whole slide
- import the image in HistoMatch
- HistoMatch automatically detects and extracts the slices, creating a scrollable slideshow
- then, the program identifies and assigns the histological slices that best fit the given atlas sections for the brain region of interest
- the next wizard step offers the versatile tools necessary for the fine adjustment/tuning between the atlas section and the corresponding histological slice (translation, rotation, anchored stretching and scaling)
- the identification and alignment procedures support the utilization of relevant landmarks, exploration traces and localization markers (e.g., iontophoretic or electrolytic depositions)
- the results of the matching procedure are exported to the main Reco application, enabling optimal correction of the trajectory-atlas spatial correlation
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